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Fetal infection by Zika virus in the third trimester – report of 2 cases

  1. Denise Cristina Mós Vaz-Oliani2,4
  1. 1Department of Radiology; Faculdade de Medicina de São José do Rio Preto - FAMERP; São José do Rio Preto, São Paulo, Brazil
  2. 2Hospital da Criança e Maternidade, São José do Rio Preto, São Paulo, Brazil
  3. 3Laboratory of Virology, Department of Infectious and Dermatological Disease, Faculdade de Medicina de São José do Rio Preto - FAMERP; São José do Rio Preto, São Paulo, Brazil
  4. 4Department of Obstetric and Gynecology; Faculdade de Medicina de São José do Rio Preto - FAMERP; São José do Rio Preto, São Paulo, Brazil
  5. 5Immunogenetics Laboratory, Department of Molecular Biology, Faculdade de Medicina de São José do Rio Preto - FAMERP, São José do Rio Preto, São Paulo, Brazil
  1. Corresponding author: Professor Mauricio Lacerda Nogueira: Laboratory of Virology, Faculdade de Medicina de São José do Rio Preto, Avenida Brigadeiro Faria Lima, 5416, 15090-000 – São José do Rio Preto, SP - Brazil, Phone: 55 17 3201-5731, E.mail: mnogueira{at}famerp.br

Abstract

Zika virus infection acquired during pregnancy was associated with congenital microcephaly. We describe two cases of ZIKV infection in the 36th week of pregnancy whose fetuses had preserved head circumference at birth and findings of subependymal cysts and lenticulostriate vasculopathy in postnatal imaging. These represent the first signs of congenital brain injury acquired due to ZIKV in the third trimester.

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