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Reply to Bernard et al

  1. Mi Suk Lee1
  1. 1Division of Infectious Diseases, Department of Internal Medicine, Kyung Hee University Hospital, Kyung Hee University School of Medicine, Seoul
  2. 2Department of Internal Medicine, Gyeongsang National University Hospital, Jinju
  3. 3Department of Infectious Diseases, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea
  1. Correspondence: M. S. Lee, Division of Infectious Diseases, Department of Internal Medicine, Kyung Hee University School of Medicine, 23, Kyungheedae-ro, Dongdaemun-gu, Seoul 130-872, Republic of Korea (mslee{at}khmc.or.kr).

To the Editor—We thank Bernard and colleagues for their comments on our recent publication [1]. In a recent randomized clinical trial [2], Bernard et al proved that 6 weeks of antibiotic treatment for vertebral osteomyelitis (VOM) was not inferior to 12 weeks of treatment. However, in our retrospective study [1], a longer duration of antibiotic therapy (≥8 weeks) lowered the recurrence rate among patients with methicillin-resistant Staphylococcus aureus (MRSA) infection or undrained paravertebral/psoas abscess. Some differences between both studies may potentially account for this discrepancy.

First, the proportion of MRSA among S. aureus causing VOM was only 5.8% in the study by Bernard et al …

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